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Michael Angell
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| Associate Professor |
B.A. Western Maryland College, 1987
Ph.D. Pennsylvania State University (Hershey), 1993
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303 Mark Jefferson |
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(734) 487-1004
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michael.angell@emich.edu
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| Biography:
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Research Interests -
My long-term interests concern how the immune system recognizes a viral infection and the tricks that some viruses use to either remain undetected or suppress an immune response. My current focus is on the interaction between papillomavirus infections and the immune system. Papillomaviruses infect many verterbrate species. In humans, they are responsible for cutaneous and genital warts as well as being strongly associated with cervical cancer. Differences in individual antiviral immune responses, which allow some animals (and people) to fight off an infection, while others remain with persistent lesions or progress to cancer, may point to common mechanism exploited by other slowly growing, or latent viruses.
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| Courses:
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| MICR 328 Introductory Microbiology |
| BIOL 204 Biology of Cancer |
| BIOL 520 Virology |
| BIOL 526 Immunobiology |
| BIOL 527 Immunobiological Methods |
| BIOL 544 Tissue Culture Techniques and Methods |
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Recent Publications: |
Hopfl,R., Christensen, N.D., Angell, M.G., Kreider, J.W. 1995. Leukocyte proliferation in vitro against cottontail rabbit papillomavirus in rabbits with persisting papillomas/cancer or after regression. Arch Dermatol Res . 287: 652-658.
Gangemi, J.D., Pifisi,L., Angell, M., Kreider, J.W. 1994. HPV replication in experimental models: effects of interferon. Antiviral Res. 24: 175-190.
Hopfl,R.M., Christensen, N.D., Angell, M.G., Kreider, J.W. 1993. Skin test to assess immunity against cottontail rabbit papillomavirus antigens in rabbits with progressing papillomas or after papilloma regression.J. Invest. Dermatol. 101:227-231.
Okabayashi, M, Angell, M.G. , Budgeon, L.R., Kreider, J.W. 1993. Shope papilloma cell and leukocyte proliferation in regressing and progressing lesions. Am.J. Pathol. 142: 489-496.
Angell, M.G., Christensen, N.D., Kreider, J.W. 1992. An in vitro system for studying the initial stages of cottontail rabbit papillomavirus (CRPV) infection. J. Virol. Methods 39: 207-216.
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