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Robert S. Winning
Professor
B.Sc., University of Calgary, 1983
M.Sc., University of Calgary, 1986
Ph.D., University of Waterloo, 1990
302 Mark Jefferson
(734) 487-4431
rwinning@emich.edu
Biography:
Research Interests -


My general research interests concern the molecular analysis of early developmental events in amphibian embryogenesis. More specifically, I am interested in how cellular interactions and cell signaling affect cell fate and cell behavior in embryos. Current research involves examination of the function of a family of receptor tyrosine kinases in embryos of the frog Xenopus laevis.
Courses:
BIOL 110 - Introductory Biology I
BIOL 223 - Human Embryonic Development
BIOL 301 - Genetics
ZOOL 323 - Animal Embryology
BIOL 540 - Cell Biology
BIOL 543 - Developmental Biology
 
Recent Publications:
Winning, R. S., Ward, E. K., Scales, J. B., and Walker, G. K., 2002. EphA4 catalytic activity causes inhibition of RhoA GTPase in Xenopus laevis embryos. Differentiation 70: 46-55.

Winning, R. S., Wyman, T. L., and Walker, G. K., 2001. EphA4 activity causes cell shape change and a loss of cell polarity in Xenopus laevis embryos. Differentiation 68: 126-132.

Winning, R.S., Scales, J.B., and Sargent, T.D., 1996. Disruption of cell adhesion in Xenopus embryos by Pagliaccio, an Eph- class receptor tyrosine kinase. Developmental Biology 179: 309-319.

Scales, J.B., Winning, R.S., Renaud, C.S., Shea, L.J., and Sargent, T.D., 1995. Novel members of the Eph receptor tyrosine kinase subfamily expressed during Xenopus development. Oncogene 11: 1745-1752.

Winning, R.S. and Sargent, T.D., 1994. Pagliaccio, a member of the Eph family of receptor tyrosine kinase genes, has localized expression in a subset of neural crest and neural tissues in Xenopus laevis embryos. Mechanisms of Development 46: 219-229.