Click on a name
Click on a name or photo at the right to go to the individuals page.Faculty and Staff in the Department of Chemistry
Ruth Ann Armitage, Ph.D. 734.487.0290
My research interests involve the analysis of archaeological materials. Current research projects include: Characterization of organic binder material in rock paintings; Characterization of 17th century brick and pottery; Radiocarbon dating of rock paintings; Surface analysis of rock painting samples.
My research interests involve the analysis of archaeological materials. Current research projects include: Characterization of organic binder material in rock paintings; Characterization of 17th century brick and pottery; Radiocarbon dating of rock paintings; Surface analysis of rock painting samples.
Timothy Brewer, Ph.D. 734.487.9613
My chief interest is in laser spectroscopy using the cavity ring-down technique and laser induced fluorescence to study the potential energy surfaces and the dynamics of molecules.
My chief interest is in laser spectroscopy using the cavity ring-down technique and laser induced fluorescence to study the potential energy surfaces and the dynamics of molecules.
Gavin Edwards, Ph.D. 734.487.0297
My research encompasses the broad issues of atmospheric chemistry, composition and dynamics. My work is focused specifically on understanding the role the biosphere has in atmospheric chemistry, particularly how biogenic emissions affect the chemistry of ozone.
My research encompasses the broad issues of atmospheric chemistry, composition and dynamics. My work is focused specifically on understanding the role the biosphere has in atmospheric chemistry, particularly how biogenic emissions affect the chemistry of ozone.
Cory Emal, Ph.D. 734.487.0305
My research interests involve the isolation, design, and synthesis of small molecule inhibitors of biological systems. My lab currently has funded projects that focus on the development of inhibitors of /Plasmodium falciparum/, the most virulent malarial parasite in humans, and of plasminogen activator inhibitor-1 (PAI-1), a human protein implicated in thrombosis, atherosclerosis, and myocardial infarction. In addition, we are also interested in the isolation and identification of PAI-1 inhibitors from natural sources, such as green tea.
My research interests involve the isolation, design, and synthesis of small molecule inhibitors of biological systems. My lab currently has funded projects that focus on the development of inhibitors of /Plasmodium falciparum/, the most virulent malarial parasite in humans, and of plasminogen activator inhibitor-1 (PAI-1), a human protein implicated in thrombosis, atherosclerosis, and myocardial infarction. In addition, we are also interested in the isolation and identification of PAI-1 inhibitors from natural sources, such as green tea.
Hedeel Evans, Ph.D. 734.487.1425
I am interested in the signal transduction pathways involved in the regulation of cell growth and proliferation in normal and neoplastic cells. The MAP kinase cascade, a coupled series of regulatory proteins, transmits signals induced by the binding of growth factors to receptors on the surface of cells.
I am interested in the signal transduction pathways involved in the regulation of cell growth and proliferation in normal and neoplastic cells. The MAP kinase cascade, a coupled series of regulatory proteins, transmits signals induced by the binding of growth factors to receptors on the surface of cells.
Timothy Friebe, Ph.D. 734.487.1423
My research interests include organic methodology and synthesis, microwave assisted organic synthesis and the application of organometallics to the synthesis of small molecules and natural products. Current projects include: the application of microwave heating to standard organic reactions and the synthetic studies of macrocyclic chelating ligands cyclen and cyclen derivatives.
My research interests include organic methodology and synthesis, microwave assisted organic synthesis and the application of organometallics to the synthesis of small molecules and natural products. Current projects include: the application of microwave heating to standard organic reactions and the synthetic studies of macrocyclic chelating ligands cyclen and cyclen derivatives.
Jeffrey Guthrie, Ph.D. 734.487.2478
My current research interests are in environmental bioanalytical/analytical chemistry. My main project is in the development of novel biosensors that use synthetic DNA fragments as probes for the detection of environmental contaminants in aquatic systems.
My current research interests are in environmental bioanalytical/analytical chemistry. My main project is in the development of novel biosensors that use synthetic DNA fragments as probes for the detection of environmental contaminants in aquatic systems.
Deborah Heyl-Clegg, Ph.D. 734.487.2057
Our group investigates peptides and structure-activity relationships. As chemical messengers of biological information, peptides present one of the most promising classes of compounds in the preliminary stages of pharmaceutical development. The goal of the peptide biochemist is to determine which portions of the peptide molecule are responsible for interacting with binding sites (receptors) to bring about a biological response.
Our group investigates peptides and structure-activity relationships. As chemical messengers of biological information, peptides present one of the most promising classes of compounds in the preliminary stages of pharmaceutical development. The goal of the peptide biochemist is to determine which portions of the peptide molecule are responsible for interacting with binding sites (receptors) to bring about a biological response.
Heather Holmes, Ph.D. 734.487.2027
My research interests involve the development of instrumentation and methods to monitor biological processes in tissue cultures in real-time. The instrument incorporates a cell incubation device with a cryofocusing inlet suitable for use with high-speed gas chromatography (GC). High-speed GC is capable of separating complex mixtures in one-tenth the time of conventional GC, on the order of seconds rather than minutes.
My research interests involve the development of instrumentation and methods to monitor biological processes in tissue cultures in real-time. The instrument incorporates a cell incubation device with a cryofocusing inlet suitable for use with high-speed gas chromatography (GC). High-speed GC is capable of separating complex mixtures in one-tenth the time of conventional GC, on the order of seconds rather than minutes.
Amy Johnson, Ph.D. 734.487.0426
My research interests involve knowledge transfer and how students are able to take what they know and apply it to help them understand novel situations or problems. Current research projects include: investigating the connections students make (and the ones they don't!) between general chemistry and introductory earth science topics.
Vance Kennedy, Ph.D. 734.487.0018
My research interests are in the field of synthetic inorganic chemistry. I am currently collaborating with researchers at Case Western Reserve University on making new phthalocyanines to be used in photodynamic tumor therapy (PDT). My current research target is the synthesis of new macrocyclic phthalocyanin compounds.
My research interests are in the field of synthetic inorganic chemistry. I am currently collaborating with researchers at Case Western Reserve University on making new phthalocyanines to be used in photodynamic tumor therapy (PDT). My current research target is the synthesis of new macrocyclic phthalocyanin compounds.
Larry Kolopajlo, Ph.D. 734.487.0100
Inorganic Chemistry - My research explores the kinetics and mechanisms of solution reactions involving these fields of coordination chemistry: (1) ligand exchange (2) metal exchange and (3) complex formation.
Chemical Education - My interests revolve around the secondary curriculum and include: outreach activities, crime scene investigation, cosmetic chemistry, animations and videos and writing in the chemistry classroom.
Inorganic Chemistry - My research explores the kinetics and mechanisms of solution reactions involving these fields of coordination chemistry: (1) ligand exchange (2) metal exchange and (3) complex formation.
Chemical Education - My interests revolve around the secondary curriculum and include: outreach activities, crime scene investigation, cosmetic chemistry, animations and videos and writing in the chemistry classroom.
Harriet Lindsay, Ph.D. 734.487.2124
My research interests revolve around the development of new synthetic methodologies and synthesis of natural products. Current research projects include: development of microwave assisted reactions and the application of these reactions to the synthesis of natural products that mimic the biological activities of sugars.
My research interests revolve around the development of new synthetic methodologies and synthesis of natural products. Current research projects include: development of microwave assisted reactions and the application of these reactions to the synthesis of natural products that mimic the biological activities of sugars.
Maria Milletti, Ph.D. 734.487.1183
My general area of research is the study of electronic structure and reactivity of molecules through molecular orbital calculations. Calculations are carried out using ab initio methods such as Hartree-Fock-Roothaan theory or Density Functional Theory. My research group usually includes several undergraduate students and the occasional graduate student. Most of the undergraduate students start their independent projects in their sophomore year.
My general area of research is the study of electronic structure and reactivity of molecules through molecular orbital calculations. Calculations are carried out using ab initio methods such as Hartree-Fock-Roothaan theory or Density Functional Theory. My research group usually includes several undergraduate students and the occasional graduate student. Most of the undergraduate students start their independent projects in their sophomore year.
Ross Nord, Ph.D. 734.487.0106
My primary interest is in studying the statistics of lattice-filling processes. In any process a site can be specified as "empty" or "filled" depending upon whether an event (reaction, adsorption,...) has occured there. Consequently, the majority of the work involves deriving kinetic equations and applying previously-developed solution techniques to obtain numerical solutions.
My primary interest is in studying the statistics of lattice-filling processes. In any process a site can be specified as "empty" or "filled" depending upon whether an event (reaction, adsorption,...) has occured there. Consequently, the majority of the work involves deriving kinetic equations and applying previously-developed solution techniques to obtain numerical solutions.
Steven Pernecky, Ph.D. 734.487.0383
Dr. Pernecky's research uses the molecular genetic techniques of site-directed mutagenisis and deletion cloning to determine the contribution of structural features and conserved amino acids to the biochemical and biophysical properties of the xenobiotic-metabolizing P450 cytochromes.
Dr. Pernecky's research uses the molecular genetic techniques of site-directed mutagenisis and deletion cloning to determine the contribution of structural features and conserved amino acids to the biochemical and biophysical properties of the xenobiotic-metabolizing P450 cytochromes.
Jamie Bruns Scaglione 734.487.3126
My research interests involve characterizing microbial enzymes responsible for synthesizing natural products. Natural products have proven to be extremely valuable to worldwide drug discovery and development programs and include compounds such as the antibiotics erythromycin and tetracyclines, the cholesterol-lowering statins, the anticancer drugs daunorubicin and epothilone, and many others...
My research interests involve characterizing microbial enzymes responsible for synthesizing natural products. Natural products have proven to be extremely valuable to worldwide drug discovery and development programs and include compounds such as the antibiotics erythromycin and tetracyclines, the cholesterol-lowering statins, the anticancer drugs daunorubicin and epothilone, and many others...
Donald Snyder, Ph.D. 734.487.1429
Our research is primarily interdisciplinary in nature, directed toward development of impedance-based electrical and wavefront-distortion based optical sensors for chemical, biochemical and materials applications. Current projects include organic synthesis of specialty monomers for functionalized polymers and self-assembled molecular monolayers on metal surfaces, investigation of microscopic interdigitated electrode arrays chips for impedance spectroscopy, and application of Shack-Hartmann ...
Our research is primarily interdisciplinary in nature, directed toward development of impedance-based electrical and wavefront-distortion based optical sensors for chemical, biochemical and materials applications. Current projects include organic synthesis of specialty monomers for functionalized polymers and self-assembled molecular monolayers on metal surfaces, investigation of microscopic interdigitated electrode arrays chips for impedance spectroscopy, and application of Shack-Hartmann ...
Jose Vites, Ph.D. 734.487.0129
Most of my projects will involve the manipulation of air-sensitive compounds using Schlenk-ware and vacuum lines, cannula and syringe techniques, a variety of chromatographic techniques (gas, plate, column, flash), and the use of infrared and 1H, 13C nuclear magnetic resonance spectroscopies. They will also involve the synthesis of organic and inorganic ligands when necessary.
Most of my projects will involve the manipulation of air-sensitive compounds using Schlenk-ware and vacuum lines, cannula and syringe techniques, a variety of chromatographic techniques (gas, plate, column, flash), and the use of infrared and 1H, 13C nuclear magnetic resonance spectroscopies. They will also involve the synthesis of organic and inorganic ligands when necessary.
Gregg Wilmes, Ph.D. 734.487.0164
My research interests involve the synthesis and study of polymeric materials. We are currently focused on developing syntheses of block copolymers under mild conditions and studying the reversible self-assembly of those materials in solution through the use of nuclear magnetic resonance spectroscopy.
My research interests involve the synthesis and study of polymeric materials. We are currently focused on developing syntheses of block copolymers under mild conditions and studying the reversible self-assembly of those materials in solution through the use of nuclear magnetic resonance spectroscopy.