Eastern Michigan University

John Carbone

Assistant Professor

312 Marshall

734.487.3303

jcarbon2@emich.edu

Education

PhD Nutritional Sciences - University of Connecticut

BS Biochemistry - Union College

Teaching Interests

Dr. Carbone's research focuses on the role of diet and exercise in maintaining skeletal muscle integrity. Specifically, he's interested in how energy balance and dietary modifications affect the activity of the ubiquitin proteasome pathway of muscle protein breakdown.

Selected Presentations and/or Publications

Carbone JW , Margolis LM, McClung JP, Cao JJ, Murphy NE, Sauter ER, Combs GF, Young AJ, Pasiakos SM. Effects of energy deficit, dietary protein, and feeding on intracellular regulators of skeletal muscle proteolysis. FASEB J. 2013; 27 [Epub ahead of print]

Pasiakos SM, Cao JJ, Margolis LM, Sauter ER, Whigham LD, McClung JP, Rood JC, Carbone JW , Combs GF Jr, Young AJ. Effects of high-protein diets on fat-free mass and muscle protein synthesis following weight loss: a randomized controlled trial. FASEB J. 2013; 27 [Epub ahead of print]

Carbone JW, Margolis LM, McClung JP, Cao JJ, Young AJ, Pasiakos SM. Energy intake modulates intramuscular mTORC1 signaling and ubiquitin-mediated proteolysis during energy deficit independent of dietary protein variations. FASEB J. 2013; 27:631.1. [abstract, poster]

Mouch EM, Walz AM, Tomaj L, Carbone JW. A randomized, crossover comparison of the effects of high fructose corn syrup versus sucrose intake on basic physiologic measures. FASEB J. 2013; 27:1074.7. [abstract, poster]

Carbone JW, Margolis LM, Cao JJ, McClung JP, Young AJ, Pasiakos SM. Acute nutrient consumption attenuates intramuscular 26S proteasome activity during energy deficit. FASEB J. 2012; 26:lb299. [abstract, poster]

Lunn WR, Pasiakos SM, Colletto MR, Karfonta KE, Carbone JW, Anderson JM, Rodriguez NR. Chocolate milk and endurance exercise recovery: protein balance, glycogen, and performance. Med Sci Sports Exerc. 2012; 44(4):682-91.

Carbone JW, McClung JP, Pasiakos SM. Skeletal muscle responses to negative energy balance: Effects of dietary protein. Adv. Nutr. 2012; 3:119-126.

Pasiakos SM, Vislocky LM, Carbone JW, Altieri N, Konopelski K, Freake HC, Anderson JM, Ferrando AA, Wolfe RR, Rodriguez NR. Acute energy deprivation affects skeletal muscle protein synthesis and associated intracellular signaling proteins in physically active adults. J Nutr. 2010. 140(4): 745-51.

Carbone JW, Pasiakos SM, Vislocky LM, Anderson JM, Rodriguez NR.  Moderate energy deprivation increases caspase-3 activity and fractional breakdown rate in human skeletal muscle. FASEB J. 2010. 24:740.19. [abstract, poster]

Lunn WR, Colletto MR, Karfonta KE, Anderson JM, Carbone JW, Rodriguez NR. Chocolate milk consumption during recovery from endurance exercise affects intracellular events of skeletal muscle protein synthesis and proteolysis. FASEB J. 2010. 24:97.1. [abstract, oral presentation]

Carbone JW, Pasiakos SM, Vislocky LM, Anderson JM, Giardina C, Bruno RS, Rodriguez NR. Moderate energy deprivation increases ubiquitin proteasome activity in physically active adults following endurance exercise. FASEB J. 2009; 23:720.1. [abstract, poster]

Pasiakos SM, Vislocky LM, Carbone JW, Freake HC, Anderson JM, Ferrando AA, Wolfe RR, Rodriguez NR. Energy-induced changes in skeletal muscle protein synthesis and molecular signaling in physically active adults. FASEB J. 2009; 23:541.2. [abstract,poster]

Vislocky LM, Pasiakos SM, Carbone JW, Freake HC, Anderson JM, Ferrando AA, Wolfe RR, Rodriguez NR. Post-exercise skeletal muscle protein synthesis and intracellular signals during negative energy balance in active adults. Med Sci Sports Exerc. 2009; 41(5):Suppl. [abstract, oral presentation]

Pasiakos SM, Konopelski KL, Vislocky LM, Carbone JW, Altieri NA, Anderson JM, Rodriguez, NR. The effect of acute energy deprivation on metabolic measures during exercise and at rest in physically active adults. Med Sci  Sports Exerc. 2008; 40(5):S472. [abstract, poster]

Pesola JM, Jahns CJ, Carbone JW, Kramer MF, Coen DM. Late genes display unexpected RNA expression profiles in the presence of acyclovir during reactivation of HSV-1 from latency. 2007; International Herpesvirus Workshop, Asheville, NC. [abstract, oral presentation]

Additional Information

Classes Taught

Dr. Carbone teaches a variety of courses within the Dietetics & Human Nutrition program, including Nutrition for Health Professionals (DTC203), Sports Nutrition (DTC204), Macronutrient Metabolism (DTC302), Research Design & Methods (DTC500), and Advanced Topics in Nutrition (DTC618).

The School of Health Sciences is part of the College of Health & Human Services, 303 Everett L. Marshall Building, 734.487.0077