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April 24, 2007 issue
Kresge Foundation grant allows biology, chemistry departments to purchase new lab equipment


By Ron Podell

 

Thanks to a $250,000 science initiative grant from the Kresge Foundation, present and future Eastern Michigan University students will be able to sort and isolate cells on a new $100,000 piece of equipment. As well as do a whole lot more.

A fluorescence activated cell sorter — one of more than 20 pieces of new lab equipment purchased with the Kresge grant and a matching amount of $500,000 raised by EMU's biology and chemistry departments through the leadership of the EMU Foundation — allows faculty and students to run a cell through a computer and tag an antibody or protein on the cell.

cell sorter

CELL SORTING: (above, from left) Mike Angell, an
associate professor of biology, and Steve Rhoades, a
biology graduate student, conduct an experiment

using the department's new fluorescence activated
cell sorter. The $102,000 piece of equipment was
one of many purchased with a $250,000
grant
from
the Kresge Foundation and $500,000 raised
by EMU's biology and chemistry departments through
the EMU Foundation.

"Now, when a group of cells runs through the machine, anything we tag can be separated into one area," explained Tamara Greco, head of the biology department. "You can look at only the cells you want to. You can conduct a purer, more isolated study of cells."

Greco also is high on the $58,500 nutrient analyzer, which, she said, can analyze nutrients in water or wetland materials in a matter of days, as opposed to months, which is the time it used to take faculty and students to sort out components through chemical testing.

"This piece of equipment has automated it all instead of a person doing each of the steps. For a place like Eastern Michigan, we actually need this equipment more because we don't have 10 graduate assistants available to mix solutions," Greco said. It does allow us to have students exposed to the latest equipment and experiences. We need students to see state-of-the-art equipment and train on it. We want students to really know what a real research experience is."

The Kresge Foundation is a $2.9 billion national foundation that builds stronger nonprofit organizations. Eastern Michigan was awarded the Kresge Foundation Science Initiative Grant in March 2006, which gave EMU's biology and chemistry departments the opportunity to purchase some much-needed scientific equipment that will make a tremendous difference in the education of EMU's students. The Kresge Foundation granted EMU $250,000 to purchase the equipment after the biology and chemistry departments raised $500,000 of its own money. Of that $500,000, American Electric Power (AEP) donated $250,000. The AEP gift was made possible by Michael Morris ('69, '73), a former EMU regent and AEP's chairman, president and CEO; and EMU foundation Trustee Dale Heydlauff ('78), vice president-New Generation, at AEP.

Greco stressed the importance of the role Patty Warner, director of corporations and foundations at the EMU Foundation, played in spearheading the effort to raise the $500,000.

"The instrumentation obtained through the Kresge Foundation Challenge Grant has greatly improved our ability to introduce students to the appropriate use of modern instrumentation," said Steve Pernecky, an associate professor of chemistry. "Specifically, we have been able to modernize our biochemistry, physical chemistry and organic chemistry laboratories."

For example, before the purchase of a new spectrophotometer, students who wanted to investigate enzyme kinetic parameters had to use a stop watch and a low-tech spectrophotometer to capture the raw data, use graph paper to determine enzyme activity for each of a dozen reactions (each reaction requires at least 10 data points), and then re-plot the data on graph paper (or using Excel) to determine the parameters, Pernecky explained.

"Now, students can directly monitor enzyme reactions, eliminating laborious manual data acquisition," he said.

The biology and chemistry departments are now in the midst of working with the EMU Foundation to raise another $1 million (AEP has donated $100,000 to this effort) to create an equipment endowment in order to receive another $250,000 check from the Kresge Foundation. When raised, the $1.25 million endowment will ensure that existing EMU lab equipment will be able to be repaired, restored or replaced in the future, Greco said.

"With our $35,000 equipment budget, we could barely buy a piece of equipment," Greco said of the department's prior situation. "In five years, some of this equipment will be obsolete or too costly to repair. By getting the Kresge initiative, we can prolong the life of equipment we purchase."