My general research interests concern the molecular analysis of early developmental events in amphibian embryogenesis. More specifically, I am interested in how cellular interactions and cell signaling affect cell fate and cell behavior in embryos. Current research involves examination of the function of a family of receptor tyrosine kinases in embryos of the frog Xenopus laevis.
Courses
BIO 110 Introductory Biology I
BIO 257 Human Embryonic Development
BIO 301 Genetics
BIO 443 Developmental Biology
BIO 540 Cell Biology
BIO 543 Developmental Biology
Achievements
Recipient of the 2010 Ron Collins Distinguished Faculty Award Winner for Teaching
Michigan Distinguished Professor of the Year, 2011
Publications and Presentations
Winning, R.S. and Krull, C.E., 2011. Knockdown of Ephrin-A5 Expression by 40% Does not Affect Motor Axon Growth or Migration into the Chick Hindlimb. Int. J. Mol. Sci. 12: 8362–8371.
Winning, R. S., Ward, E. K., Scales, J. B., and Walker, G. K., 2002. EphA4 catalytic activity causes inhibition of RhoA GTPase in Xenopus laevis embryos. Differentiation 70: 46–55.
Winning, R. S., Wyman, T. L., and Walker, G. K., 2001. EphA4 activity causes cell shape change and a loss of cell polarity in Xenopus laevis embryos. Differentiation 68: 126–132.
Winning, R.S., Scales, J.B., and Sargent, T.D., 1996. Disruption of cell adhesion in Xenopus embryos by Pagliaccio, an Eph-class receptor tyrosine kinase. Developmental Biology 179: 309–319.
Scales, J.B., Winning, R.S., Renaud, C.S., Shea, L.J., and Sargent, T.D., 1995. Novel members of the Eph receptor tyrosine kinase subfamily expressed during Xenopus development. Oncogene 11: 1745–1752.