Department of Chemistry

Courses

• CHEM 115, 2011
• CHEM 116, 2011 (long-term substitute)

Publications and Presentations

1. "Revisiting [PtCL2(cis-1,4-DACH)]: An Underestimated Antitumor Drug with Potential Application to the Treatment of Oxaliplatin-Refractory Colorectal Cancer", J. Med. Chem., 55 (16), 7182–7192(2012). Nicola Margiotta, Cristina Marzano, Valentina Gandin, Domenico Psella, Maruo Ravera, Emanuele Petruzzella, James D. Hoeschele, and Giovanni Natile.
2. "Biography of Dr. Barnett Rosenberg" Anticancer Res. 34 (1) 417–421 (2014)
3. "Serendipity and the Prepared Mind; The Discovery of the Antitumor Drug, Cisplatin", J. Inorg. Biochem. (Submitted, 1/14)
4. "Pre-clinical Characterization of STAT3 Small Molecule Inhibitors for Primary and Metastatic Brain Cancer Therapy". J. Biol. Chem., Hikmat Assi, Chris Paran, Jon Savakus, James D. Hoeschele, Nathan VanderVeen, Robert Doherty, Henry Appelman, Leda Raptis, Tom Mikkelsen, Pedro R. Lowenstein and Maria G. Castro. (To be submitted, 2/14).
5. Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin and Other Platinum Complexes. Matthew D. Hall, Katherine A. Telma, Ki-Eun Chang, Tobie D. Lee, John Lloyd, Ian G., James D. Hoeschele (Submitted, 1/27/14)
6. "Microwave-Assisted Synthesis of Cisplatin", with Cristian Chirosca and Emanuele Petruzzella. (In preparation)
7. "Unique Reactivity of Kiteplatin with S-donor Biomolecules and DNA Models." (with Emanuele Petruzzella, Nicola Margiotta, and Giovanni Natile)(To be submitted to J. Biol. Chem., 2/14)
8. PATENT (Provisional)- March 15, 2013 "Method of Treating Colorectal Cancer", filed March 15, 2013. A formal patent application will be submitted on or by March 15, 2014. (In collaboration with two research groups from Italy.)