Tod Holler
Education
- BS, Harvey Mudd College, 1978
- Ph.D., University of Washington, 1989
- Postdoctoral Fellow, Massachusetts Institute of Technology, 1989–1991
Interests and Expertise
- Organic Chemistry
- Enzymology
Industrial Experience
- Parke-Davis Pharmaceutical Research, Ann Arbor, MI, 1991–2000
- Pfizer Global Research and Development, Ann Arbor, MI, 2000–2007
- Pfizer Global Research, Sandwich, UK, 2007–2010
Courses
- CHEM 121 General Chemistry I
- CHEM 122 General Chemistry Laboratory
- CHEM 120 Fundamentals of Organic and Biochemistry
- CHEM 271 Organic Chemistry Laboratory
Publications and Presentations
- Mosberg, JA, Yep A, Meredith TC, Smith S, Wan, P-F. Holler TP, Mobley HLT, Woodard RW. A Unique Arabinose 5-Phosphate Isomerase Found within a Genomic Island Associated with the Uropathogenicity of Escherichia coli CFT073. Journal of Bacteriology 2011;193:298-2988.
- Oduor RO, Ojo KK, Williams Gareth P, Bertelli F, Mills J, Maes L, Pryde DC, Parkinson, T, Van Voorhis WC, Holler TP. Trypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leads. PLOS Neglected Diseases 2011;5(4):e1017.
- Gabrielli L, Merlo S, Airoldi C, Sperandeo P, Gianera S, Polissi A, Nicotra F, Holler TP, Woodard RWCipolla L. Arabinose 5-phosphate isomerase as a target for antibacterials design: Studies with substrate analogues and inhibitors. Bioorgic and Medicinal Chemistry 2014;22(8):2576-2583.
- Li C., Li W., Holler T. P., Gu Z, Li Z. Polyethylene glycols enhance the thermostability of cyclodextrin glycosyltransferase from Bacillus circulans. Food Chemistry 2014;164;17-22.
- Li Z., Huang M, Gu Z, Holler TP, Cheng L, Hong Y, Li C. Asp577 mutation enhance the catalytic efficiency of cyclodextrin glycosyltransferase from Bacillus circulans. Int. J. Biol. Macromol. 2016; 83:111-116.
Professional Affiliations
- American Chemical Society
- American Society for Biochemistry and Molecular Biology
- American Medical Writers Association