Tod Holler

A photo of Tod Holler

Part-Time Lecturer


501A Science Complex


[email protected]


  • BS, Harvey Mudd College, 1978
  • Ph.D., University of Washington, 1989
  • Postdoctoral Fellow, Massachusetts Institute of Technology, 1989–1991

Interests and Expertise

  • Organic Chemistry
  • Enzymology
Industrial Experience
  • Parke-Davis Pharmaceutical Research, Ann Arbor, MI, 1991–2000
  • Pfizer Global Research and Development, Ann Arbor, MI, 20002007
  • Pfizer Global Research, Sandwich, UK, 20072010


  • CHEM 121 General Chemistry I
  • CHEM 122 General Chemistry Laboratory
  • CHEM 120 Fundamentals of Organic and Biochemistry
  • CHEM 271 Organic Chemistry Laboratory

Publications and Presentations

  • Mosberg, JA, Yep A, Meredith TC, Smith S, Wan, P-F. Holler TP, Mobley HLT, Woodard RW. A Unique Arabinose 5-Phosphate Isomerase Found within a Genomic Island Associated with the Uropathogenicity of Escherichia coli CFT073. Journal of Bacteriology 2011;193:298-2988.
  • Oduor RO, Ojo KK, Williams Gareth P, Bertelli F, Mills J, Maes L, Pryde DC, Parkinson, T, Van Voorhis WC, Holler TP. Trypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leads. PLOS Neglected Diseases 2011;5(4):e1017.
  • Gabrielli L, Merlo S, Airoldi C, Sperandeo P, Gianera S, Polissi A, Nicotra F, Holler TP, Woodard RWCipolla L. Arabinose 5-phosphate isomerase as a target for antibacterials design: Studies with substrate analogues and inhibitors. Bioorgic and Medicinal Chemistry 2014;22(8):2576-2583.
  • Li C., Li W., Holler T. P., Gu Z, Li Z. Polyethylene glycols enhance the thermostability of cyclodextrin glycosyltransferase from Bacillus circulans. Food Chemistry 2014;164;17-22.
  • Li Z., Huang M, Gu Z, Holler TP, Cheng L, Hong Y, Li C. Asp577 mutation enhance the catalytic efficiency of cyclodextrin glycosyltransferase from Bacillus circulans. Int. J. Biol. Macromol. 2016; 83:111-116.

Professional Affiliations

  • American Chemical Society
  • American Society for Biochemistry and Molecular Biology
  • American Medical Writers Association